Doctors Recommend Carefully Treat Tinnitus. Part 3 of 3

Doctors Recommend Carefully Treat Tinnitus – Part 3 of 3

For the 20-day treatment period, vagus nerve stimulation was paired with half-second moral tones that ranged in frequency from 170 hertz to 16000 hertz (cycles per second). Tones were always at least a half-octave above or below ear-ringing frequencies. In the end, the researchers said the patients master few side effects, and that the four patients who experienced relief from their condition had maintained their improvements as much as two months after therapy.

None of the four had been taking any medications during the study period, the authors said. By contrast, the five patients who failed to go through relief had been taking a range of medications. Dr Donald Keamy Jr, a pediatric otolaryngologist (ear, nose and throat specialist) at the Massachusetts Eye and Ear Infirmary, said the striving addresses a real need for new tinnitus treatments.

He was not involved with the study. “Many people try to ignore this condition when it arises, but this is a very prevalent problem. And while we have treatments, there’s no one analysis that fits everybody. In fact, many sufferers, like the ones in this study, have tried everything and nothing has worked.

Which means, frustratingly, that many people who seek advise are told that they just have to live with it, even though they can’t sleep and they can’t perform their daily duties. So this can be very debilitating, and have a really big impact on a patient’s quality of life click here. The traditional treatments we have are not enough and a search for new approaches – like this one – is certainly necessary”.

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Doctors Recommend Carefully Treat Tinnitus. Part 2 of 3

Doctors Recommend Carefully Treat Tinnitus – Part 2 of 3

According to the US National Institute on Deafness and Other Communication Disorders, nearly 23 million American adults have at some projection struggled with ear ringing for periods extending beyond three months. Yet tinnitus is not considered to be a malady in itself, but rather an indication of trouble somewhere along the auditory nerve pathway. Noise-sparked hearing loss can set off ringing, as can ear/sinus infection, brain tumors, heart disease, hormonal imbalances, thyroid problems and medical complications.


A swarm of treatments are available. The two most notable are “cognitive behavioral therapy” (to promote relaxation and mindfulness) and “tinnitus retraining therapy” (to essentially false flag the ringing with more neutral sounds). In 2012, a Dutch team investigated a combination of both approaches, and found that the combined therapy process did seem to reduce flaw and improve patients’ quality of life better than either intervention alone.

Additional options include neural stimulation, hearing aids, cochlear implants, dietary adjustments, and/or antidepressants and anti-anxiety medications. But there is no known cure, and some patients do not react to any treatment. Searching for a new approach, the investigators behind the new study focused on a small group of just 10 Belgian patients, all of whom had been struggling with tough ear-ringing for a minimum of one year before enrolling in the study Dec 2013.

Standard treatments had failed to ease their symptoms. Each patient was implanted with a stimulation electrode connected directly to their vagus nerve. The analyse team noted that electrical stimulation of the vagus nerve is already approved by the US Food and Drug Administration as a method for treating both epilepsy and depression. Throughout the 2,5 hours of day after day treatment, electrical stimulation levels remained below 1 percent of the FDA-approved maximum, according to the study.

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Doctors Recommend Carefully Treat Tinnitus. Part 1 of 3

Doctors Recommend Carefully Treat Tinnitus – Part 1 of 3

Doctors Recommend Carefully Treat Tinnitus. Patients pain from the intense, chronic and sometimes untreatable ringing in the ear known as tinnitus may get some relief from a new combination therapy, prelude research suggests. The study looked at treatment with daily targeted electrical stimulation of the body’s nervous system paired with sound therapy. Half of the procedure – “vagus impertinence stimulation” – centers on direct stimulation of the vagus nerve, one of 12 cranial nerves that winds its way through the abdomen, lungs, heart and brain stem.

Patients are also exposed to “tone therapy” – carefully selected tones that invention outside the frequency range of the troubling ear-ringing condition. Indications of the new treatment’s success, however, are so far based on a very slight pool of patients, and relief was not universal. “Half of the participants demonstrated large decreases in their tinnitus symptoms, with three of them showing a 44 percent reduction in the impact of tinnitus on their daily lives,” said read co-author Sven Vanneste.

But, “five participants, all of whom were on medications for other problems, did not show significant changes”. For those participants, drug interactions might have blocked the therapy’s impact, Vanneste suggested. “However, further analysis needs to be conducted to confirm this,” said Vanneste, an associate professor at the School of Behavioral and Brain Sciences at the University of Texas at Dallas. The study, conducted in collaboration with researchers at the University Hospital Antwerp, in Belgium, appeared in a latest issue of the journal Neuromodulation: Technology at the Neural Interface.

The authors disclosed that two members of the study team have a superintend connection with MicroTransponder Inc, the manufacturer of the neurostimulation software used to deliver vagus nerve stimulation therapy. One researcher is a MicroTransponder employee, the other a consultant. Vanneste himself has no connection with the company.

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The Researchers Have Found A Way To Treat Ovarian Cancer. Part 3 of 3

The Researchers Have Found A Way To Treat Ovarian Cancer – Part 3 of 3

Because the test is still experimental, Bielas could not estimate what the test might fetch if it were eventually approved and used widely in patients. Right now the test isn’t ready for general use, according to Dr Franck Pages, a professor of immunology at the Hospital European Georges Pompidou in Paris, and framer of an accompanying journal editorial. “The new technology does not obviously fulfill the requirements for an easy routine clinical use to quantify T-cell infiltration in a tumor but the technology could advise in immunotherapy trials to determine the immunological response induced in the tumor”.

Another expert agreed that more work must be done before the test can be used clinically. “It’s been known for some time that there is a correlation between the level of natural hit man cells – T-cells – and the prognosis of patients,” said William Chambers, interim national vice president for extramural research at the American Cancer Society. “There is affluent to be a need for other people to verify the findings from this study. There is also a need to figure out how this would fit in the context of any sort of clinical approach” extenze. More information To find out more about the immune system and cancer, descend upon the US National Cancer Institute.

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The Researchers Have Found A Way To Treat Ovarian Cancer. Part 2 of 3

The Researchers Have Found A Way To Treat Ovarian Cancer – Part 2 of 3

Our technology is comparable to a barcode scanner”. The technique, called QuanTILfy, was tested on tumor samples from 30 women with ovarian cancer whose survival ranged from one month to about 10 years. Bielas and colleagues looked at the thousand of TILs in the tumors, comparing those numbers to the women’s survival. The researchers found that higher TIL levels were linked with better survival.


For example, the percent of TILs was about three times higher in women who survived more than five years than in those who survived less than two years. “We are hoping to study whether this is a accepted phenomena of all cancers. There is good evidence now that the same associations can be made for melanoma and colorectal cancer”. This renewed technology potentially could be used to predict treatment response, cancer recurrence and disease-free survival earlier and more effectively than current methods.

It could therefore be used to guide personalized medicine. For example, it could be utilized to determine which immune and chemotherapy drugs are best to treat a particular patient, Bielas suggested. “Thus, TIL can be used to guide the selection of drugs for cancer therapy, thereby improving passive outcome. The implementation of this assay in the clinic should improve cancer diagnostics and ultimately save lives.

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The Researchers Have Found A Way To Treat Ovarian Cancer. Part 1 of 3

The Researchers Have Found A Way To Treat Ovarian Cancer – Part 1 of 3

The Researchers Have Found A Way To Treat Ovarian Cancer. By counting the enumerate of cancer-fighting immune cells inside tumors, scientists approximately they may have found a way to predict survival from ovarian cancer. The researchers developed an experimental method to count these cells, called tumor-infiltrating T lymphocytes (TILs), in women with initially stage and advanced ovarian cancer. “We have developed a standardizable method that should one day be available in the clinic to better inform physicians on the best course of cancer therapy, therefore improving treatment and patient survival,” said direct researcher Jason Bielas, at the Fred Hutchinson Cancer Research Center, in Seattle.

The test may have broader implications beyond ovarian cancer and be useful with other types of cancer, the ponder authors suggested. In their current work with ovarian cancer patients, the researchers “demonstrated that this method can be used to diagnose T-cells quickly and effectively from a blood sample,” said Bielas, an accessory member in human biology and public health sciences. The report was published online Dec 4, 2013 in Science Translational Medicine.

The researchers developed the try to count TILs, identify their frequency and develop a system to determine their ability to clone themselves. This is a way of measuring the tumor’s population of immune T-cells. The test factory by collecting genetic information of proteins only found in these cells. “T-cell clones have unique DNA sequences that are comparable to product barcodes on items at the grocery store.

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Worries About Job Losses Increase The Chances Of Heart Attack And Stroke. Part 3 of 3

Worries About Job Losses Increase The Chances Of Heart Attack And Stroke – Part 3 of 3

Dr Suzanne Steinbaum, director of Women and Heart Disease at Lenox Hill Hospital in New York City, said: “This is the from the start time that we are seeing the realities of the fact that women are in the workforce just as much as men but oftentimes are not in a position of management. And it’s not just necessarily working but the nature of what the job is like”.

It should be noted that this bookwork highlighted an apparent association between job stress and heart trouble for women, and did not prove a cause and effect. A second study, also presented at the meeting, found that, if you’re a woman, there may be such a thing as sleeping too long, although literary perchance not sleeping too little, when it comes to heart health.

Researchers at the Harvard School of Public Health tracked the sleep habits and stroke incidence of almost 70000 women for 20 years. They reported that women who slept for 10 hours or more had a 63 percent higher peril of suffering a stroke, and a 55 percent hiked risk when other factors such as blood pressure were enchanted into account. Women who slept seven hours – the median amount of sleep reported in the study – had the lowest risk of stroke. Short sleep duration didn’t seem to matter: Even women who slept six or fewer hours a evening were not at heightened stroke risk, the researchers reported browser. Previous research had suggested the opposite, the research team noted.

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